Publications by authors named "J Moilanen"
Objectives: According to the manufacturer, the Hemochron ACT-LR cuvette is designated for heparin concentrations of 0 to 2.5 IU/mL, while the optimal concentration range for the ACT+ cartridge is 1 to 6 IU/mL. We hypothesized that at low to moderate heparin concentrations, the ACT-LR is more reliable than the ACT+.
View Article and Find Full Text PDFArticle Synopsis
- * Manually labeling unstructured medical reports for DR analysis is labor-intensive, leading to the development of DR-GPT, a large language model designed to classify DR severity from these reports.
- * DR-GPT demonstrated high accuracy in severity classification and improved the performance of image classifiers when its annotations were combined with fundus images, showcasing the potential of AI in healthcare.
Purpose: To analyze central corneal in vivo confocal microscopy (IVCM) in Terrien marginal degeneration (TMD).
Methods: An observational prospective case-control study. Ten Finnish patients with TMD from a tertiary referral center were compared with 10 age- and sex-matched healthy volunteers.
The -acyl-ω-hydroxy fatty acids (OAHFAs) are an intriguing class of surface-active lipids which can be found in the human tear film lipid layer (TFLL). Recent studies have suggested that OAHFAs exist in the polar lipid layer and play a central role in TFLL function. Surprisingly, biophysical profiling studies have only shed light on the properties of OAHFAs bearing an oleate acyl group and insights on species with other acyl groups are scarce.
View Article and Find Full Text PDFSi nanoparticles (NPs) have been actively developed as a hyperpolarized magnetic resonance imaging (MRI) contrast agent with an imaging window close to one hour. However, the progress in the development of NPs has been hampered by the incomplete understanding of their structural properties that correspond to efficient hyperpolarization buildup and long polarization decays. In this work we study dynamic nuclear polarization (DNP) of single crystal porous Si (PSi) NPs with defined doping densities ranging from nominally undoped to highly doped with boron or phosphorus.
View Article and Find Full Text PDF