Publications by authors named "J Moal"
Objective: Childhood hyperthyroidism is mostly caused by Graves' disease, a rare autoimmune disease in children. Epidemiological data are scarce and the variability of within-region incidence is unknown. We aimed to provide the first description of temporal trends in pediatric hyperthyroidism in France and to explore spatial trends, with a view to identifying possible environmental triggers.
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- Endometriosis is a hormone-dependent disease that may be influenced by environmental factors, prompting a nationwide study in France to analyze spatial trends between 2011 and 2017.
- The study identified over 207,000 new cases of hospitalized endometriosis, with a notable increase in incidence rates during the specified period, particularly among non-adenomyosis cases.
- Researchers found geographical variations in risk, pinpointing 20 high-risk areas and suggesting that better diagnosis, increased awareness, and possible environmental factors may contribute to these trends.
Study Question: Is there an evolution in the risk of operated cryptorchidism in France and does local geographical environment appear as an important trigger for this defect?
Summary Answer: We observed an increase of the risk of operated cryptorchidism in boys under the age of 7 years during the period 2002-2014 and a strong spatial heterogeneity, with the detection of spatial clusters suggesting environmental factors.
What Is Known Already: Epidemiologic data on cryptorchidism are scarce and its etiology is poorly understood. As part of the testicular dysgenesis syndrome, cryptorchidism is suspected to be a male genital developmental disorder caused by endocrine disruptor chemical (EDC) exposure during the prenatal period.