MicroRNAs are non-coding transcripts that, thanks to the ability to regulate the mRNA of target genes, can affect the expression of genes encoding tumor suppressors and oncogenes. They can control many important cellular processes, including apoptosis, differentiation, growth, division, and metabolism. Therefore, miRNAs play an important role in the development of many cancers, including gynecological cancers.
View Article and Find Full Text PDFIn this paper, the multifractal properties of the ion current time series in the fast-activating vacuolar (FV) channels of L. taproot cells were investigated. These channels are permeable for only monovalent cations and mediate K at very low concentrations of cytosolic Ca and large voltages of either polarity.
View Article and Find Full Text PDFThe economy is a system of complex interactions. The COVID-19 pandemic strongly influenced economies, particularly through introduced restrictions, which formed a completely new economic environment. The present work focuses on the changes induced by the COVID-19 epidemic on the correlation network structure.
View Article and Find Full Text PDFONQUADRO is an advanced database system that supports the study of the structures of canonical and non-canonical quadruplexes. It combines a relational database that collects comprehensive information on tetrads, quadruplexes, and G4-helices; programs to compute structure parameters and visualise the data; scripts for statistical analysis; automatic updates and newsletter modules; and a web application that provides a user interface. The database is a self-updating resource, with new information arriving once a week.
View Article and Find Full Text PDFWithin the paper, the problem of globalisation during financial crises is analysed. The research is based on the Forex exchange rates. In the analysis, the power law classification scheme (PLCS) is used.
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