Publications by authors named "J Miranda Mallea"

Article Synopsis
  • In Pavlovian conditioning, the strength of responses depends on the probability of reinforcement, but this study controlled for reinforcement rates to better understand this relationship.
  • Two experiments with mice showed that varying the probability of reinforcement influenced response rates during training and extinction phases, even when the overall reinforcement rate was constant.
  • The findings suggest that both the probability of reinforcement and the rate at which it is delivered play important roles in behavior, challenging existing learning theories to incorporate these factors more effectively.
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Objective: Innovative technology such as normothermic regional perfusion and the Organ Care System has expanded donation after circulatory death heart transplantation. We wanted to investigate the impact of donation after circulatory death heart procurement in concurrent lung donation and implantation at a national level.

Methods: We reviewed the United Network for Organ Sharing database for heart donation between December 2019 and March 2022.

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Follow-up of patients with emphysema treated with endobronchial valves is limited to 3-12 months after treatment in prior reports. To date, no comparative data exist between treatment and control subjects with a longer follow-up. To assess the durability of the Spiration Valve System (SVS) in patients with severe heterogeneous emphysema over a 24-month period.

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Background: In the US, only 23% of lungs offered for transplantation are transplanted. Ex vivo lung perfusion (EVLP) allows for evaluation of additional donor lungs; its adoption has been limited by resources and expertise. Dedicated facilities with a centralized lung evaluation system (CLES) could expand access to EVLP.

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Article Synopsis
  • * A meta-analysis of 34 studies involving 736 patients indicated that MSC therapy led to lower all-cause mortality and serious adverse events when compared to control groups.
  • * Further research with larger, double-blinded randomized controlled trials is necessary to confirm these findings and fully assess the efficacy and safety of MSC therapies in this context.
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