Publications by authors named "J Minic"
Article Synopsis
- Selective bromelain-based enzymatic debridement (BED) is effective for treating severe burns (TBSA > 20%), addressing the challenge of limited donor sites for skin grafting.
- A study analyzed nine burn patients who received BED followed by the modified Meek micro-grafting technique, focusing on their outcomes, complications, and overall recovery.
- Results showed that most patients survived, experienced fewer complications, and had better scar quality with the combined techniques compared to traditional grafting methods.
ECONOMIC ANALYSIS OF ENZYMATIC DEBRIDEMENT VERSUS STANDARD BURN CARE: A RETROSPECTIVE ANALYSIS.
Ann Burns Fire Disasters
June 2024
When compared to standard surgical management, rapid enzymatic debridement of deep burns reduces the need for surgery while achieving similar long-term results. However, few studies have directly compared the costs of standard surgical and enzymatic burn care. We conducted a study comparing the care costs of 44 adult burn patients treated before (n=22) and after (n=22) introducing rapid bromelain-based enzymatic debridement (BED) of deep burns.
View Article and Find Full Text PDFThe COVID-19 pandemic necessitated and facilitated the introduction of telework in organizations. This has also impacted the workers' relationship between work and private life. The aim of the current study was to examine the links between resilience and mode of work (stationary vs.
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- Nexobrid®, a bromelain-based enzymatic debridement, is increasingly recommended for burn treatment based on expert input from Italian burn centers.* -
- A consensus panel of Italian experts, using the Delphi method, reached almost full agreement on the guidelines for using enzymatic debridement, with 24 out of 27 statements receiving strong consensus.* -
- The resulting recommendations are tailored to the Italian context and will evolve over time with new evidence, enhancing the existing literature on burn surgery practices.*
At the neuromuscular junction (NMJ) acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) can hydrolyze acetylcholine (ACh). Released ACh quanta are known to diffuse rapidly across the narrow synaptic cleft and pairs of ACh molecules cooperate to open endplate channels. During their diffusion through the cleft, or after being released from muscle nicotinic ACh receptors (nAChRs), most ACh molecules are hydrolyzed by AChE highly concentrated at the NMJ.
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