Publications by authors named "J Minhas"
Article Synopsis
- The article describes the creation of the first ultrasound system for continuous monitoring of brain tissue pulsations (BTPs) using transcranial Doppler (TCD) technology.
- A lightweight, wearable probe called Transcranial Tissue Doppler (TCTD) was developed to measure tissue motion and was tested successfully with existing TCD hardware.
- The new system, Brain Tissue Velocimetry (Brain TV), can capture BTP data in real-time alongside other vital physiological measurements and shows potential for clinical assessment in healthy and stroke patients.
Background: Increased epicardial adipose tissue (EAT) has adverse effects in cardiovascular diseases, independent of body mass index (BMI). Estrogen levels may impact EAT accumulation. Little is known about the predictors and potential impact of EAT in PAH.
View Article and Find Full Text PDFObjective: Remote patient monitoring (RPM) beat-to-beat blood pressure (BP) provides an opportunity to measure poststroke BP variability (BPV), which is associated with clinical stroke outcomes. BP sampling interval (SI) influences ambulatory BPV, but RPM BP SI optimisation research is limited. SI and RPM device capabilities require compromises, meaning SI impact requires investigation.
View Article and Find Full Text PDFSubcomponent analysis of the directional sensitivity of dynamic cerebral autoregulation.
Am J Physiol Heart Circ Physiol
January 2025
Article Synopsis
- The study investigates the unknown origin of directional sensitivity (DS) in dynamic cerebral autoregulation (dCA) using measurements from 140 healthy participants, focusing on middle cerebral artery velocity (MCAv) and arterial blood pressure (ABP).
- Results show that MCAv and resistance-area product (RAP) exhibit significant directional sensitivity in response to changes in mean arterial pressure (MAP), while critical closing pressure (CrCP) does not.
- The findings suggest that the directional sensitivity in cerebral blood flow is likely myogenic (related to muscle response) and is primarily mediated by RAP, indicating minimal influence from metabolic factors or sympathetic nervous system control.