Publications by authors named "J Michelle Njoroge"

Importance: Heart failure (HF) and frailty frequently coexist and may share a common pathobiology, although the underlying mechanisms remain unclear. Understanding these mechanisms may provide guidance for preventing and treating both conditions.

Objective: To identify shared pathways between incident HF and frailty in late life using large-scale proteomics.

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Article Synopsis
  • Crack use is notably higher in the UK compared to other European countries, particularly among people who inject drugs (PWID), with a significant increase in crack injection reported from 2011 to 2021.
  • The study found that crack injection is more common among males and is often done alongside heroin, with behaviors like sharing needles and injecting in the groin increasing risks for blood-borne viruses and infections.
  • The findings highlight the urgent need for harm reduction strategies and drug treatment programs to address the rising prevalence of crack injection and its associated health risks.
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Objectives: This study explores trends in sex work among people who inject drugs (PWID) by gender and the relationship between sex work and adverse health outcomes including overdose, injection-site, and blood-borne virus (BBV) infections.

Study Design: The Unlinked Anonymous Monitoring Survey of PWID is an annual cross-sectional survey that monitors BBV prevalence and behaviours, including transactional sex, among PWID recruited through specialist services in England, Wales, and Northern Ireland.

Methods: Trends in sex work among PWID (2011-2021) were described.

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Background: Omecamtiv mecarbil improves cardiovascular outcomes in patients with heart failure (HF) with reduced ejection fraction (EF). Consistency of drug benefit across race is a key public health topic.

Objectives: The purpose of this study was to evaluate the effect of omecamtiv mecarbil among self-identified Black patients.

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