Publications by authors named "J Michael Janda"
Background: Many studies have demonstrated the association between low birth weight (LBW) and chronic kidney disease, estimated glomerular filtration rate (eGFR) and kidney volume (KV). However, studies on twins and those investigating numerous perinatal factors beyond LBW, and their associations with various kidney parameters are scarce.
Methods: A two-center cross-sectional study on five-year-old LBW children was conducted between 2021 and 2023.
Article Synopsis
- - Since the 1960s, over 350,000 new chemicals have been introduced, impacting both humans and animals, yet our understanding of their health risks is still limited.
- - The "epithelial barrier theory" indicates that genetic factors and various exposures lead to damaged epithelial barriers, contributing to allergic and autoimmune diseases in both humans and pets.
- - This review highlights the effects of impaired epithelial barriers on companion animals, discussing the rise of less regulated cosmetic and food products for pets, and aligns with the "One Health" concept, emphasizing the connection between human, animal, and environmental health.
Article Synopsis
- Mitochondrial dysfunction, inflammation, fibrosis, and cell aging play significant roles in the transition from acute kidney injury (AKI) to chronic kidney disease, although the specific cellular processes involved are still being studied.
- Recent research has identified key factors at the single-cell level that affect the repair processes in the kidneys after ischemia-reperfusion injury, with a focus on the role of the drug lasmiditan.
- The study found that lasmiditan treatment enhances the expression of genes associated with successful kidney repair and reduces the expression of maladaptive repair genes, suggesting it could be a promising therapeutic option for improving kidney recovery after AKI.
The genus , previously residing in the family Enterobacteriaceae and now a member of the family , is currently composed of five species, although the taxonomy of this genus is still unsettled. The genus can primarily be divided into two pathogenic groups: strains are responsible for almost all human infections, and two other species (, ) cause diseases in fish. Human infections predominate in subtropical habitats of the world and in specific geospatial regions with gastrointestinal disease, bloodborne infections, and wound infections, the most common clinical presentations in decreasing order.
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