Publications by authors named "J Michael Collaco"

Objective: To investigate the link between outpatient respiratory outcomes in children with bronchopulmonary dysplasia (BPD) who are prescribed outpatient diuretics versus those who are not at the time of their initial pediatric pulmonary clinic visit.

Study Design: Patient data were gathered by chart review and validated questionnaires on 1,002 children with BPD discharged between 2008 and 2023 seen at the Children's Hospital of Philadelphia and Johns Hopkins Children's Center outpatient pediatric pulmonary clinics.

Results: Children prescribed outpatient diuretics (n=634) at time of first pulmonary appointment were more likely to have severe BPD and require home supplemental oxygen.

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Rationale: Extremely preterm infants are at highest risk for developing bronchopulmonary dysplasia (BPD). This study aimed to examine the relationship between gestational age and respiratory outcomes in children with BPD in the outpatient setting.

Methods: Data were collected from 1025 preterm children with BPD recruited from outpatient bronchopulmonary (BPD) clinics at Johns Hopkins and Children's Hospital of Philadelphia (CHOP).

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Rationale: Chronic () airway infection is common and a key contributor to diminished lung function and early mortality in persons with cystic fibrosis (PwCF). Risk factors for chronic among PwCF include cystic fibrosis transmembrane conductance regulator genotype, genetic modifiers, and environmental factors. Intensive antibiotic therapy and highly effective modulators do not eradicate in most adolescents and adults with cystic fibrosis.

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Background: There is a substantial population of long-stay patients who non-emergently transfer directly from the neonatal intensive care unit (NICU) to the pediatric intensive care unit (PICU) without an interim discharge home. These infants are often medically complex and have higher mortality relative to NICU or PICU-only admissions. Given an absence of data surrounding practice patterns for non-emergent NICU to PICU transfers, we hypothesized that we would encounter a broad spectrum of current practices and a high proportion of dissatisfaction with current processes.

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Article Synopsis
  • - The study focuses on bronchopulmonary dysplasia (BPD), a common chronic respiratory issue in infants, particularly those born preterm, highlighting the lack of consistent clinical care guidelines.
  • - A survey of 27 BPD programs revealed significant variability in outpatient care, including referral processes, services offered, follow-up echocardiograms, and discharge criteria.
  • - The authors advocate for the creation of comprehensive clinical guidelines for BPD, similar to those for asthma and cystic fibrosis, to standardize care and potentially improve long-term health outcomes.
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