Non-surgical treatment of peri-implantitis.

Treatment of peri-implantitis follows similar steps as the therapy of periodontitis. Non-surgical interventions, however, show limited success and in many cases, don't lead to a complete resolution of the local inflammation. The scientific literature was evaluated and based on the European Federation of Periodontology's S3-level guideline, recommendations for clinical practice are presented.

Periodontal disease: A systemic condition.

For decades, periodontitis has been considered to be a local inflammatory disease of the periodontal tissues in the oral cavity. Initially, associations of periodontitis with a multitude of noncommunicable diseases were each studied separately, and relationships were shown. The associations of periodontitis with morbidities, such as cardiovascular diseases, rheumatoid arthritis, diabetes mellitus, respiratory diseases, have been demonstrated.

The role of the oral microbiota in the causal effect of adjunctive antibiotics on clinical outcomes in stage III-IV periodontitis patients.

Background: Periodontitis, a prevalent chronic inflammatory disease, offers insights into the broader landscape of chronic inflammatory conditions. The progression and treatment outcomes of periodontitis are closely related to the oral microbiota's composition. Adjunctive systemic Amoxicillin 500 mg and Metronidazole 400 mg, often prescribed thrice daily for 7 days to enhance periodontal therapy's efficacy, have lasting effects on the oral microbiome.