Publications by authors named "J Messer"
Background And Aims: Alcohol-associated hepatitis (AH) is the most life-threatening form of alcohol-associated liver disease (ALD). AH is characterized by severe inflammation attributed to increased levels of ethanol, microbes or microbial components, and damage-associated molecular pattern (DAMP) molecules in the liver. HSPB1 (Heat Shock Protein Family B (Small) Member 1; also known as Hsp25/27) is a DAMP that is rapidly increased in and released from cells experiencing stress, including hepatocytes.
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- Pelvic organ prolapse after radical cystectomy is difficult to treat, with high chances of recurrence due to weakened pelvic floor support and tissue quality, particularly after colpocleisis procedures.
- A 64-year-old woman with a history of radical cystectomy faced recurrent stage IV vaginal prolapse and underwent a novel robotic-assisted vaginal hernia repair using a polypropylene-reinforced tissue matrix due to unsuitable vaginal tissue for traditional repairs.
- The surgery resulted in no complications, improved her prolapse severity, and enhanced her overall health and quality of life post-recovery, indicating it as a viable treatment option for similar cases.
Introduction: Use of indocyanine green (ICG) with near-infrared fluorescence (NIRF) has been demonstrated to be an effective tool for intraoperative assessment of bowel and ureteric vascularity. This study aimed to evaluate the impact of ICG on postsurgical outcomes such as anastomotic bowel leak and uretero-enteric stricture formation during robot-assisted cystectomy (RAC) and intracorporeal urinary diversion (ICUD).
Methods: We identified 238 patients who underwent RAC at the University of Louisville between September 2012 and August 2021.
Introduction: The increasing adoption of robotic-assisted cystectomy with intracorporeal urinary diversion (ICUD), despite its complexity, prompts a detailed comparison with extracorporeal urinary diversion (ECUD). Our study at a single institution investigates perioperative outcomes and identifies risk factors impacting the success of these surgical approaches.
Methods: In this retrospective analysis, 174 patients who underwent robotic-assisted cystectomy at the University of Louisville from June 2016 to August 2021 were reviewed.