Publications by authors named "J Meschke"

The United States Centers for Disease Control and Prevention reported a rise in resistant infections after the coronavirus disease 2019 (COVID-19) pandemic started. How and if the pandemic contributed to antibiotic resistance in the larger population is not well understood. Wastewater treatment plants are good locations for environmental surveillance because they can sample entire populations.

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Article Synopsis
  • - The COVID-19 pandemic emphasized the importance of using quantitative microbial risk assessment (QMRA) for enhancing public health protection through modeling infectious disease risks.
  • - A recent workshop gathered 41 QMRA experts to outline crucial research priorities such as improving methods, harmonizing environmental monitoring, and integrating different scientific approaches.
  • - Key recommendations include building a collaborative research community, enhancing data collection efforts, and ensuring sustainable funding to support the advancement of QMRA for global health policies.
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Article Synopsis
  • Salmonella enterica serovar Typhi (S. Typhi) causes Typhoid fever, and while blood cultures are the best way to diagnose it, they're hard to use in resource-limited areas.* -
  • Researchers developed a novel process control organism (PCO) as a biosafe surrogate to test various environmental surveillance methods for detecting S. Typhi in water.* -
  • The PCO successfully mimicked S. Typhi in lab tests and was consistently detected in wastewater samples from India and Malawi, making it a reliable tool for validating environmental detection methods for this pathogen.*
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Article Synopsis
  • * Environmental surveillance is crucial for tracking the presence of S. Typhi in wastewater, but factors like pathogen decay and laboratory methods create uncertainty in results.
  • * This study introduces a computational model that combines dynamic and probabilistic methods to improve the estimation and monitoring of S. Typhi in wastewater, aiding in effective environmental surveillance in endemic areas.
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