Publications by authors named "J Meister"
Background: Ciliary neurotrophic factor (CNTF), mainly known for its neuroprotective properties, belongs to the IL-6 (interleukin-6) cytokine family. In contrast to IL-6, the effects of CNTF on the vasculature have not been explored. Here, we examined the role of CNTF in AngII (angiotensin II)-induced hypertension.
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- High salt (HS) intake can worsen immune responses and contribute to the development of hypertensive vascular diseases, particularly after exposure to Ang II, a hormone that raises blood pressure.
- In experiments with mice, a short period of HS consumption led to increased inflammation and a higher occurrence of severe vascular issues when combined with Ang II infusion, despite no blood pressure differences between groups.
- The study concludes that transient HS intake triggers a mild immune response that becomes problematic when followed by Ang II exposure, suggesting that HS acts as a precursor to more significant hypertension-related health risks.
Noise from unmanned aerial vehicles, commonly referred to as "drones," will likely shape our acoustic environment in the near future. Yet, reactions of the population to this new noise source are still little explored. The objective of this study was to investigate short-term noise annoyance reactions to drones in a controlled laboratory experiment.
View Article and Find Full Text PDFChronic hyperglycemia induces intrarenal oxidative stress due to the excessive production of reactive oxygen species (ROS), leading to a cascade of events that contribute to the development and progression of diabetic kidney disease (DKD). NOX5, a pro-oxidant NADPH oxidase isoform, has been identified as a significant contributor to renal ROS in humans. Elevated levels of renal ROS contribute to endothelial cell dysfunction and associated inflammation, causing increased endothelial permeability, which can disrupt the renal ecosystem, leading to progressive albuminuria and renal fibrosis in DKD.
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