Publications by authors named "J McWhae"

Objective: The purpose of this guideline update is to reassess and update recommendations in the prior guideline from 2016 on the appropriate management of patients with uveal melanoma.

Methods: In 2021, a multidisciplinary working group from the Provincial Cutaneous Tumour Team, Cancer Care Alberta, Alberta Health Services was convened to update the guideline. A comprehensive review of new research evidence in PubMed as well as new clinical practice guidelines from prominent oncology groups informed the update.

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Article Synopsis
  • Uveal melanoma survival rates have not improved since the 1970s, emphasizing the importance of early and accurate diagnosis for better treatment outcomes.
  • A consensus-based guideline was developed through expert discussions and extensive literature review, leading to recommendations for managing this complex condition.
  • Key management strategies include staging with serum and imaging tests, enucleation for large tumors, and radiotherapy as the primary treatment, while encouraging clinical trial participation for patients with metastatic disease.
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Purpose: To report a case of an idiopathic unilateral filtering bleb in an otherwise well patient and a case of bilateral spontaneous filtering blebs in association with Terrien marginal degeneration.

Methods: In this retrospective observational study of 2 cases, clinical notes, ultrasound biomicroscopy and gonioscopy images were reviewed.

Results: Case 1: A 32-year-old woman presented with a 1-year history of a gradually growing cyst in her right eye.

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