Publications by authors named "J McHugh"
Background: Physical forces exerted by expanding brain tumors - specifically the compressive stresses propagated through solid tissue structures - reduces brain perfusion and neurological function, but heretofore has not been directly measured in patients . Solid stress levels estimated from tumor growth patterns are negatively correlated with neurological performance in patients. We hypothesize that measurements of solid stress can be used to inform clinical management of brain tumors.
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- Twisted two-dimensional (2D) material heterostructures allow researchers to explore unique physical phenomena, especially at small twist angles where crystals rearrange themselves.
- Understanding these complex materials requires advanced imaging techniques to visualize the local configurations, which can vary due to disorder.
- The study presents an effective method using electron channeling contrast imaging (ECCI) to non-destructively visualize these domains in twisted transition metal dichalcogenide (TMD) heterostructures, even under encapsulation layers, enhancing insight into their properties.
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- * Recent research used advanced genetic sequencing techniques to uncover a new fusion gene (CRTC1::MAML2) and a surprising rearrangement of the MAML2 gene to MYBL1, hinting at MYBL1's potential role in salivary gland cancers.
- * The study also found that TERT gene rearrangements and amplifications are common in MEC tumors, with TERT playing a crucial role in tumor growth, as demonstrated
: is an uncommon pathogen that has been reported to infect musculoskeletal structures. However, studies are largely limited to case reports, and little is known regarding management and outcomes of these infections. : We performed a multicenter retrospective cohort study of adults with culture-confirmed musculoskeletal infections at three Mayo Clinic centers in Arizona, Florida, and Minnesota from November 2011 through April 2022.
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