Implementing a shared decision-making intervention to support treatment decisions for patients following an anterior cruciate ligament rupture - a protocol for the POP-ACLR feasibility study.

Background: Treatment for anterior cruciate ligament (ACL) rupture may follow a surgical or nonsurgical pathway. At present, there is uncertainty around treatment choice. Two shared decision-making tools have been codesigned to support patients to make a decision about treatment following an ACL rupture.

Systematic review of the patient burden of generalised myasthenia gravis in Europe, the Middle East, and Africa.

Background: Myasthenia gravis (MG) is a rare autoimmune disease characterised by muscle weakness, and progression from ocular (oMG) to generalised (gMG) symptoms results in a substantial negative impact on quality of life (QoL). This systematic review aimed to provide an overview of the patient burden experienced by people living with gMG.

Methods: Electronic database searches (conducted March 2022), supplemented by interrogation of grey literature, were conducted to identify studies reporting patient burden outcomes in patients with gMG in Europe, the Middle East and Africa.

Cognitive failure in patients with terminal cancer: a prospective study.

In a prospective open study, 61 consecutive patients with terminal cancer admitted to the hospital underwent cognitive assessment using the Mini-Mental State Questionnaire three times a week between admission and discharge or death. Mini-Mental State Questionnaire score upon admission was 28 +/- 1.5 in patients who were discharged (N = 14), and 25 +/- 3 in patients who died in the hospital (N = 47, P less than 0.

Preoperative cardiac evaluation.

A thorough history and a complete physical examination will detect most cardiac problems that can affect perioperative management or outcome. Further diagnostic tests, including an electrocardiogram, a chest radiograph and more sophisticated studies, should be performed if indicated by the history and physical examination. Congestive heart failure and a myocardial infarction within the six months before surgery are the most important risk factors for postoperative cardiac events, but almost all cardiovascular diseases have some impact on perioperative management and risk stratification.