Publications by authors named "J Mazela"
Background And Objective: The effects of neonatal hypoglycemia on the developing brain are well known, resulting in poor neurological outcomes. We aimed to perform an updated meta-analysis on neonatal hypoglycemia, the severity of hypoglycemia, and the associated neurodevelopmental outcomes from infancy to adulthood.
Methods: A systematic literature search was conducted from inception until March 2024, using the PubMed, CINAHL, Embase, and the CENTRAL databases.
Article Synopsis
- Surfactant therapy has proven highly effective for both preterm and term infants, especially those less than 28 weeks gestation, reducing their vulnerability and improving treatment outcomes.
- A subgroup analysis shows that using less invasive surfactant administration techniques (LISA/MIST) significantly lowers the need for mechanical ventilation by 28% and decreases the incidence of bronchopulmonary dysplasia (BPD) by 30% compared to traditional methods like intubation-surfactant-extubation (INSURE).
- The review emphasizes the need for personalized treatment approaches based on individual patient data, while no significant difference in mortality rates was found between the different surfactant administration methods.
Introduction: Premature and low-birthweight infants are at especially high risk of perinatal complications, including impaired thermoregulation, infections and respiratory distress. Such adverse effects and the need for invasive procedures are associated with high mortality among preterms. This study focused on the influence of the innate immune system and tested the levels of collectins, collectin-10 (CL-10), collectin-11 (CL-11) and mannose-binding lectin (MBL) in preterm neonates.
View Article and Find Full Text PDFImportance: Compared with early cord clamping (ECC), umbilical cord milking (UCM) reduces delivery room cardiorespiratory support, hypoxic-ischemic encephalopathy, and therapeutic hypothermia in nonvigorous near-term and full-term infants. However, UCM postdischarge outcomes are not known.
Objective: To determine the 2-year outcomes of children randomized to UCM or ECC at birth in the Milking in Nonvigorous Infants (MINVI) trial.
Article Synopsis
- Respiratory syncytial virus (RSV) is a major reason for hospitalizing young children in Poland, particularly those under 5 years old.
- A study analyzed data from public hospitals between July 2015 and June 2023, revealing that RSV hospitalizations increased every season, including during and after the COVID-19 pandemic.
- The highest hospitalization rates were found in infants, especially those aged 2-3 months, and a notable rise in hospitalizations for older age groups followed the pandemic, altering the traditional seasonal patterns of RSV infections.