Effects of Manganese Carbonate Addition on the Carbocatalytic Properties of Lignocellulosic Waste for Use in the Degradation of Acetaminophen.

A carbon-based material was synthesized using potato peels (BPP) and banana pseudo-stems (BPS), both of which were modified with manganese to produce BPP-Mn and BPS-Mn, respectively. These materials were assessed for their ability to activate peroxymonosulfate (PMS) in the presence of MnCO to degrade acetaminophen (ACE), an emerging water contaminant. The materials underwent characterization using spectroscopic, textural, and electrochemical techniques.

Biomechanical Evaluation of Physical Examination Tests for Rotator Cuff Tears - A Computer Simulation Study.

Background: Numerous physical diagnostic shoulder tests have been established to determine the presence of rotator cuff tears and to identify the affected muscles. However, reported sensitivities and specificities of these tests vary strongly. The aim of this study was to identify diagnostic postures that are biomechanically most sensitive in identifying rotator cuff lesions and compensation mechanisms.

Harnessing Oxetane and Azetidine Sulfonyl Fluorides for Opportunities in Drug Discovery.

Four-membered heterocycles such as oxetanes and azetidines represent attractive and emergent design options in medicinal chemistry due to their small and polar nature and potential to significantly impact the physiochemical properties of drug molecules. The challenging preparation of these derivatives, especially in a divergent manner, has severely limited their combination with other medicinally and biologically important groups. Consequently, there is a substantial demand for mild and effective synthetic strategies to access new oxetane and azetidine derivatives and molecular scaffolds.

Preliminary reference values for Alzheimer's disease plasma biomarkers in Congolese individuals with and without dementia.

Background: Western countries have provided reference values (RV) for Alzheimer's disease (AD) plasma biomarkers, but there are not available in Sub-Saharan African populations.

Objective: We provide preliminary RV for AD and other plasma biomarkers including amyloid- (Aβ42/40), phosphorylated tau-181 and 217 (p-tau181, p-tau217), neurofilament light (Nfl), glial fibrillary acidic protein (GFAP), interleukin 1b and 10 (IL-1b and IL-10) and tumor necrosis factor (TNFα) in Congolese adults with and without dementia.

Methods: 85 adults (40 healthy and 45 dementia) over 50 years old were included.

Automatic three-dimensional analysis of posterosuperior full-thickness rotator cuff tear size on MRI.

Background: Tear size and shape are known to prognosticate the efficacy of surgical rotator cuff (RC) repair however, current manual measurements on magnetic resonance images (MRI), exhibit high interobserver variabilities and exclude three-dimensional (3D) morphological information. This study aimed to develop algorithms for automatic 3D analyses of posterosuperior full-thickness RC tear to enable efficient and precise tear evaluation and 3D tear visualization.

Methods: - A deep-learning network for automatic segmentation of the tear region in coronal and sagittal multicenter MRI was trained with manually segmented (consensus of 3 experts) pd- and T2 weighted MRI of shoulders with full-thickness posterosuperior tears (n=200).