Publications by authors named "J Mattysen"
Context: The use of foetal tissue is an emotive issue and attempts are being made to find suitable alternative replacements. A duct ligated pancreas resembles day 16-17 post-coitum foetal pancreas tissue, both being predominantly endocrine structures.
Objective: The aim of this study was to quantify the metabolic changes occurring in chemically induced diabetic rats over a 30 day period following transplantation of duct ligated tissue beneath the renal capsule.
Context: Ligation of the pancreatic duct, distally to its confluence into the bile duct has been shown to induce endocrine tissue regeneration. The surplus endocrine tissue formed is presumed to be able to replace pathologically and/or experimentally compromised tissue.
Objective: This is a quantitative study on the histology of duct ligated pancreas employing immunocytochemistry and computerised morphometry.