Publications by authors named "J Matenga"

Article Synopsis
  • - A study was conducted to see if clinical guidelines for warfarin dosing could be practically applied to black Zimbabwean patients.
  • - Out of 62 patients, 62.90% did not get the recommended starting dose of warfarin according to guidelines from the Clinical Pharmacogenetics Implementation Consortium (CPIC).
  • - CPIC guidelines consider African-specific genetic variations, making them more suitable for Zimbabwean patients compared to US FDA and Dutch guidelines, which do not account for these variants.
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Background: Approximately 25% of colorectal cancer patients in sub-Saharan Africa are younger than 40 years, and hereditary factors may contribute. We investigated the frequency and patterns of inherited colorectal cancer among black Zimbabweans.

Methods: A population-based cross-sectional study of ninety individuals with a new diagnosis of colorectal cancer was carried out in Harare, Zimbabwe between November 2012 and December 2015.

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Background: The rising incidence of colorectal cancer in sub-Saharan Africa may be partly caused by changing dietary patterns. We sought to establish the association between dietary patterns and colorectal cancer in Zimbabwe.

Methods: One hundred colorectal cancer cases and 200 community-based controls were recruited.

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The interplay between hereditary and environmental factors in the causation of colorectal cancer in sub-Saharan Africa is poorly understood. We carried out a community based case-control study to identify the risk factors associated with colorectal cancer in Zimbabwe. We recruited 101 cases of colorectal cancer and 202 controls, matched for age, sex and domicile.

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Background: Sub-Saharan Africa has an inadequate number of health professionals, leading to a reduced capacity to respond to health challenges, including HIV/AIDS. From 2010 to 2015, the Medical Education Partnership Initiative (MEPI)-sponsored by the U.S.

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