Integrated interdisciplinary workflows for research on historical newspapers: Perspectives from humanities scholars, computer scientists, and librarians.

This article considers the interdisciplinary opportunities and challenges of working with digital cultural heritage, such as digitized historical newspapers, and proposes an integrated digital hermeneutics workflow to combine purely disciplinary research approaches from computer science, humanities, and library work. Common interests and motivations of the above-mentioned disciplines have resulted in interdisciplinary projects and collaborations such as the NewsEye project, which is working on novel solutions on how digital heritage data is (re)searched, accessed, used, and analyzed. We argue that collaborations of different disciplines can benefit from a good understanding of the workflows and traditions of each of the disciplines involved but must find integrated approaches to successfully exploit the full potential of digitized sources.

Effects of growth and exercise on composition, structural maturation and appearance of osteoarthritis in articular cartilage of hamsters.

Articular cartilage composition and structure are maintained and remodeled by chondrocytes under the influence of loading. Exercise-induced changes in the composition, structure, mechanical properties and tissue integrity of growing and aging hamster articular cartilage were investigated. Articular cartilage samples (n = 191) were harvested from the proximal tibiae of hamsters aged 1, 3, 6, 12 and 15 months.

Biomechanical, biochemical and structural correlations in immature and mature rabbit articular cartilage.

Objective: The structure and composition of articular cartilage change during development and growth. These changes lead to alterations in the mechanical properties of cartilage. In the present study, biomechanical, biochemical and structural relationships of articular cartilage during growth and maturation of rabbits are investigated.

Comparison of single-phase isotropic elastic and fibril-reinforced poroelastic models for indentation of rabbit articular cartilage.

Classically, single-phase isotropic elastic (IE) model has been used for in situ or in vivo indentation analysis of articular cartilage. The model significantly simplifies cartilage structure and properties. In this study, we apply a fibril-reinforced poroelastic (FRPE) model for indentation to extract more detailed information on cartilage properties.