Publications by authors named "J Manez-Miro"
Article Synopsis
- The subthalamic nucleus (STN) plays a key role in the functioning of the basal ganglia and is important in understanding Parkinson's disease (PD).
- Research showed that targeting specific areas of the STN through focused ultrasound can improve different motor symptoms of PD, such as bradykinesia, rigidity, and tremors.
- The study's findings support the idea that distinct pathways in the brain are responsible for various PD symptoms, highlighting the complex relationship between subthalamic and cortical connections in motor control and disease progression.
Social cognition (SC) encompasses a set of cognitive functions that enable individuals to understand and respond appropriately to social interactions. Although focused ultrasound subthalamotomy (FUS-STN) effectively treats Parkinson's disease (PD) clinical motor features, its impact and safety on cognitive-behavioral interactions/interpersonal awareness are unknown. This study investigated the effects of unilateral FUS-STN on facial emotion recognition (FER) and affective and cognitive theory of mind (ToM) in PD patients from a randomized sham-controlled trial (NCT03454425).
View Article and Find Full Text PDFImportance: Unilateral magnetic resonance imaging (MRI)-guided focused ultrasound subthalamotomy (FUS-STN) improves cardinal motor features among patients with asymmetrical Parkinson disease (PD). The feasibility of bilateral FUS-STN is as yet unexplored.
Objective: To assess the safety and effectiveness of staged bilateral FUS-STN to treat PD.
Unilateral focused ultrasound subthalamotomy in early Parkinson's disease: a pilot study.
J Neurol Neurosurg Psychiatry
February 2024
Background: Unilateral focused ultrasound subthalamotomy (FUS-STN) improves motor features of Parkinson's disease (PD) in moderately advanced patients. The less invasive nature of FUS makes its early application in PD feasible. We aim to assess the safety and efficacy of unilateral FUS-STN in patients with PD of less than 5 years from diagnosis (early PD).
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