Terphenyl-Ge as μ-Ge-bis(hexahapto-Trip) Bridging Ligand to Form a New Transition Metal-Only Chelating Lewis Base.

Terphenylgermanium Ar*Ge [Ar*=CH(2,6-Trip), Trip=2,4,6-CHiPr] was found to act as a novel μ-Ge-bis(hexahapto-Trip) bridging ligand. Deprotonated terphenyl germanium trihydride [Li(thf)][Ar*GeH] (1) undergoes reductive elimination and transfer of hydrogen in reaction with dimeric [(COD)RhCl] to yield the dinuclear complex [Ar*GeRh(COE)RhCl(COD)] (2). Subsequent chloride abstraction from compound 2 using Na[BAr ] or Li[Al(OBu)] results in the cationic complexes [Ar*GeRh(COE)Rh(COD)][WCA] (3) {WCA: [BAr ] (Ar=CH-3,5-(CF)), [Al(OBu)]}.

Selective Hydrodeoxygenation of Lignin-Derived Phenols to Aromatics Catalyzed by NbO-Supported Iridium.

The dominating catalytic approach to aromatic hydrocarbons from renewables, deoxygenation of phenol-rich depolymerized lignin bio-oils, is hard to achieve: hydrodeoxygenation (HDO) of phenols typically leads to the loss of aromaticity and to non-negligible fractions of cyclohexanones and cyclohexanols. Here, we report a catalyst, niobia-supported iridium nanoparticles (Ir@NbO), which combines full conversion in the HDO of lignin-derived phenols with appreciable and tunable selectivity for aromatics (25-95%) under mild conditions (200-300 °C, 2.5-10 bar of H).

Advancements in capacitance-to-digital converter-based C D technology for detection in capillary electrophoresis using amplified excitation voltages and comparison to classical and open-source C Ds.

This work introduces new hardware configurations for a capacitively coupled contactless conductivity detector (C D) based on capacitance-to-digital conversion (CDC) technology for CE. The aim was to improve sensitivity, handling, price, and portability of CDC-based C D detectors (CDCD) to reach LODs similar to classic C Ds with more sophisticated electric circuits. To achieve this, a systematic study on the CDCDs was carried out including a direct comparison to already established C D setups.

Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h.

Haematopoietic stem and progenitor cells (HSPCs) have been the focus of developmental and regenerative studies, yet our understanding of the signalling events regulating their specification remains incomplete. We demonstrate that supt16h, a component of the Facilitates chromatin transcription (FACT) complex, is required for HSPC formation. Zebrafish supt16h mutants express reduced levels of Notch-signalling components, genes essential for HSPC development, due to abrogated transcription.

Implications of Left-sided Gallbladder in the Emergency Setting: Retrospective Review and Top Tips for Safe Laparoscopic Cholecystectomy.

Background: Left-sided gallbladder without situs viscerum inversus (LSG-woSVI) is a rare congenital anomaly. Clinical features and routine presurgical imaging could miss the anomalous position, thereby producing complications during surgery. Laparoscopic cholecystectomy can be performed safely, but the risk of bile duct injury (BDI) is greater than in cholecystectomy of the orthotopic gallbladder.