Publications by authors named "J Mancilla-Ramirez"

Introduction: The increasing overuse of antibiotics in recent years has led to antibiotics being the most prescribed drugs for pediatric patients, and 72% of patients in the neonatal intensive care unit are treated with antibiotics. One effect of antibiotic use is the alteration of the microbiota, which is associated with metabolic disorders, including obesity.

Methods: This experimental study in newborn rats compared the administration of ampicillin/meropenem (Access/Watch groups) at 100/10 μg/g every 12 h, cefotaxime 200 μg/g every 24 h (Watch group), and amikacin 15 μg/g every 24 h (Access group) versus saline solution as the control.

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Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this process. Today, these vesicles have been characterized, and it has been determined that the cargo they transport is not within a random system.

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Article Synopsis
  • Obesity is linked to chronic inflammation which can lead to cognitive issues and neurodegenerative diseases due to factors like adipokines, high lipid, and glucose levels.
  • The study aims to explore how these factors cause gliosis in obese individuals and suggests antioxidants as a potential treatment for reducing neuroinflammation.
  • Research was conducted through extensive database searches to understand the relationship between obesity, gliosis, and the role of antioxidants in managing these issues.
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Mental health is defined as the ability by which individuals recognize their own abilities and cope with the normal stress of life, work productively and fruitfully, contribute to their communities and enjoy the greatest possible well-being. Therefore, it is essential as a part of the health of the individual and its constant evaluation. Recently, special attention has been drawn to the study of the mental health of women, given the greater probability to suffer depression and anxiety disorders during and after pregnancy.

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