Diagnostic accuracy of a novel method for detection of acute transmural myocardial ischemia based upon a self-applicable 3-lead configuration.

Background: Delayed medical attendance is a leading cause of death in patients with ST elevation myocardial infarction (STEMI).

Methods: We aimed to introduce, develop, and validate a novel method (RELF method) for detection of transmural ischemia based on a new and easy-to-use 3-lead configuration and orthonormalization of ST reference vectors (STDVN). The study included 60 patients undergoing coronary artery occlusion (CAO) during balloon inflation and 30 healthy subjects.

A shape-based quality evaluation and reconstruction method for electrical impedance tomography.

Linear methods of reconstruction play an important role in medical electrical impedance tomography (EIT) and there is a wide variety of algorithms based on several assumptions. With the Graz consensus reconstruction algorithm for EIT (GREIT), a novel linear reconstruction algorithm as well as a standardized framework for evaluating and comparing methods of reconstruction were introduced that found widespread acceptance in the community. In this paper, we propose a two-sided extension of this concept by first introducing a novel method of evaluation.

The solution for the independence of bioelectric and biomagnetic signals is confirmed.

The theoretical solution for the independence of bioelectric and biomagnetic signals rising from volume sources was published by Jaakko Malmivuo in 1995 [1]. In 2000 his research group published a clinical study on electro- and magnetocardiography which confirmed this result [2, 3]. In 2005 Iwasaki and co-workers published a clinical study on the detection of epileptic foci with electro- and magnetoencephalo-graphy [4].

Comparison of the properties of EEG and MEG in detecting the electric activity of the brain.

Since the detection of the first biomagnetic signals in 1963 there has been continuous discussion on the properties and relative merits of bioelectric and biomagnetic measurements. In this review article it is briefly discussed the early history of this controversy. Then the theory of the independence and interdependence of bioelectric and biomagnetic signals is explained, and a clinical study on ECG and MCG that strongly supports this theory is presented.