Gas phase Elemental abundances in Molecular cloudS (GEMS) II. On the quest for the sulphur reservoir in molecular clouds: the HS case.

Context: Sulphur is one of the most abundant elements in the Universe. Surprisingly, sulphuretted molecules are not as abundant as expected in the interstellar medium and the identity of the main sulphur reservoir is still an open question.

Aims: Our goal is to investigate the HS chemistry in dark clouds, as this stable molecule is a potential sulphur reservoir.

Development of Large-Scale Downstream Processing for Lentiviral Vectors.

The interest in lentiviral vectors (LVs) has increased prominently for gene therapy applications, but few have reached the later stages of clinical trials. The main challenge has remained in scaling up the manufacturing process for the fragile vector to obtain high titers for usage. We have previously scaled up the LV production to iCELLis 500, being able to produce up to 180 L of harvest material in one run with perfusion.

Skewing of the glottal flow with respect to the glottal area measured in natural production of vowels.

In the production of voiced speech, glottal flow skewing refers to the tilting of the glottal flow pulses to the right, often characterized as a delay of the peak, compared to the glottal area. In the past four decades, several studies have addressed this phenomenon using modeling of voice production with analog circuits and computer simulations. However, previous studies measuring flow skewing in natural production of speech are sparse and they contain little quantitative data about the degree of skewing between flow and area.

Gas phase Elemental abundances in Molecular cloudS (GEMS): I. The prototypical dark cloud TMC 1.

GEMS is an IRAM 30m Large Program whose aim is determining the elemental depletions and the ionization fraction in a set of prototypical star-forming regions. This paper presents the first results from the prototypical dark cloud TMC 1. Extensive millimeter observations have been carried out with the IRAM 30m telescope (3 mm and 2 mm) and the 40m Yebes telescope (1.

Compressible flow simulations of voiced speech using rigid vocal tract geometries acquired by MRI.

Voiced speech consists mainly of the source signal that is frequency weighted by the acoustic filtering of the upper airways and vortex-induced sound through perturbation in the flow field. This study investigates the flow instabilities leading to vortex shedding and the importance of coherent structures in the supraglottal region downstream of the vocal folds for the far-field sound signal. Large eddy simulations of the compressible airflow through the glottal constriction are performed in realistic geometries obtained from three-dimensional magnetic resonance imaging data.