Real-time execution of SNN models with synaptic plasticity for handwritten digit recognition on SIMD hardware.

Recent advancements in neuromorphic computing have led to the development of hardware architectures inspired by Spiking Neural Networks (SNNs) to emulate the efficiency and parallel processing capabilities of the human brain. This work focuses on testing the HEENS architecture, specifically designed for high parallel processing and biological realism in SNN emulation, implemented on a ZYNQ family FPGA. The study applies this architecture to the classification of digits using the well-known MNIST database.

Real-time hardware emulation of neural cultures: A comparative study of in vitro, in silico and in duris silico models.

Biological neural networks are well known for their capacity to process information with extremely low power consumption. Fields such as Artificial Intelligence, with high computational costs, are seeking for alternatives inspired in biological systems. An inspiring alternative is to implement hardware architectures that replicate the behavior of biological neurons but with the flexibility in programming capabilities of an electronic device, all combined with a relatively low operational cost.

The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation.

Thousand-and-one-amino acid kinase 3 (TAOK3) is a serine and threonine kinase that belongs to the STE-20 family of kinases. Its absence reduces T cell receptor (TCR) signaling and increases the interaction of the tyrosine phosphatase SHP-1, a major negative regulator of proximal TCR signaling, with the kinase LCK, a component of the core TCR signaling complex. Here, we used mouse models and human cell lines to investigate the mechanism by which TAOK3 limits the interaction of SHP-1 with LCK.

NOD2 Agonism Counter-Regulates Human Type 2 T Cell Functions in Peripheral Blood Mononuclear Cell Cultures: Implications for Atopic Dermatitis.

Atopic dermatitis (AD) is known as a skin disease; however, T cell immunopathology found in blood is associated with its severity. Skin () and associated host-pathogen dynamics are important to chronic T helper 2 (Th2)-dominated inflammation in AD, yet they remain poorly understood. This study sought to investigate the effects of -derived molecules and skin alarmins on human peripheral blood mononuclear cells, specifically testing Th2-type cells, cytokines, and chemokines known to be associated with AD.

Design, fabrication, characterization and reliability study of CMOS-MEMS Lorentz-force magnetometers.

This article presents several design techniques to fabricate micro-electro-mechanical systems (MEMS) using standard complementary metal-oxide semiconductor (CMOS) processes. They were applied to fabricate high yield CMOS-MEMS shielded Lorentz-force magnetometers (LFM). The multilayered metals and oxides of the back-end-of-line (BEOL), normally used for electronic routing, comprise the structural part of the MEMS.