GPIHBP1 increase accounts for rheumatic arthritis-related hypotriglyceridemia by facilitating lipids uptake of white adipose tissues.

Background: Metabolism alteration is a common complication of rheumatic arthritis (RA). This work investigated the reason behind RA-caused triglyceride (TG) changes.

Methods: Fresh RA patients' whole blood was transfused into NOD-SCID mice.

Characteristics and environmental significance of sulfur isotope signatures in the water environment of typical pyrite mines.

Contaminants in the water environment of different pyrite mines have varying characteristics due to different geological origins. Sulfur isotope (δS) is an effective tool to reveal the mechanism of water environment contamination, but no investigations have yet analyzed the characteristics and environmental significance of the δS in the water environment of different pyrite mines. This study involved a field investigation of four typical pyrite mines in China (representing volcanic, skarn, sedimentary-metamorphic, and coal-deposited types) and the analysis of the hydrochemistry of aqueous samples and the δS of both pyrite and dissolved sulfates.

Gluteus medius contracture: A case report and review of the literature.

Rationale: Bilateral gluteus medius contractures in adults are rare in clinical practice, with only a few cases reported. These contractures may result from repeated intramuscular injections during childhood. Understanding the clinical manifestations, diagnostic process, treatment, and outcomes can provide insights into effective management strategies.

Research progress on the relationship between fine motor skills and academic ability in children: a systematic review and meta-analysis.

Background: In recent years, an increasing number of scholars have begun to focus on the relationship between children's motor development and school activities, with the relationship between children's fine motor skills and academic achievement being a particularly researched area. However, due to different research perspectives among scholars, the results in this field have been somewhat controversial. Therefore, this study aims to delve deeper into the relationship between children's fine motor skills and their various academic abilities through systematic review and meta-analysis.

NEDD4 family E3 ligases in osteoporosis: mechanisms and emerging potential therapeutic targets.

Osteoporosis is a systemic skeletal disorder characterized by reduced bone density and an increased risk of fractures, particularly prevalent in the aging population. Osteoporotic complications, including vertebral compression fractures, hip fractures, and distal forearm fractures, affect over 8.9 million individuals globally, placing a significant economic strain on healthcare systems.