Publications by authors named "J M Zingg"

Article Synopsis
  • - The vaginal microbiome plays a crucial role in women's health and can be influenced by various life stages and health conditions, similar to the gut microbiome.
  • - Quorum sensing is a communication process among bacteria and fungi that triggers harmful behaviors like biofilm formation and virulence, but the specifics of how these microbes interact remain unclear.
  • - Researchers are exploring quorum quenchers as a potential treatment to disrupt harmful biofilm formation in the vagina, potentially enhancing the effectiveness of antibiotics against bacterial and fungal infections.
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Endometriosis is a disease affecting approximately 10% of reproductive age women. Loss of the tumor suppressor gene AT-rich interactive domain-containing protein 1A (ARID1A) occurs in some endometriosis cases. Histone deacetylase 6 (HDAC-6) is an enzyme with implication in several diseases including different cancer types and immunological disorders, where it is involved in protein trafficking and degradation, cell shape, and migration.

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Article Synopsis
  • Curcumin, found in turmeric, is recognized for its potential health benefits, including anti-cancer and anti-inflammatory properties, but its absorption in the body may be too low to be effective.
  • Dietary sources alone may not provide sufficient curcumin levels, leading researchers to explore methods to enhance its bioavailability, such as using nanoparticles.
  • Increasing curcumin levels might boost its health benefits, particularly its antioxidant effects, but it also requires careful monitoring to avoid negative impacts on cellular functions.
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Article Synopsis
  • * The biosensor uses a modified green fluorescent protein (GFP) with a copper-binding motif that generates a detectable fluorescence signal when it interacts with copper.
  • * Tested in both liquid and soil environments, the biosensor achieved detection limits of 0.27 mg/L in solution and 1.26 mg/kg in soil, demonstrating its effectiveness for field applications.
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