Publications by authors named "J M Woulfe"

Article Synopsis
  • Scientists have been studying a mysterious part of the nervous system called the neuronal intranuclear rodlet (INR) for over a century, first discovered by early researchers like Santiago Ramon y Cajal.
  • This review discusses the history, significance, and recent findings about the INR, especially its strange behavior in diseases like Alzheimer's.
  • The authors reveal that these rodlets are actually bundles of a special enzyme and suggest that this new understanding could change how we look at brain cells in modern science.
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The majority of patients with Parkinson disease (PD) experience a loss in their sense of smell and accumulate insoluble α-synuclein aggregates in their olfactory bulbs (OB). Subjects affected by a SARS-CoV-2-linked illness (COVID-19) also frequently experience hyposmia. We previously postulated that microglial activation as well as α-synuclein and tau misprocessing can occur during host responses following microbial encounters.

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