Publications by authors named "J M Wojcik"
Background: Curcuminoids, the bioactive compounds found in turmeric, exhibit potent antioxidant, anti-inflammatory, and neuroprotective properties. This study aims to enhance the extraction of curcuminoids from turmeric using environmentally friendly solvents supercritical CO (scCO) combined with natural deep eutectic solvents (NADESs) in one process, and to evaluate the resulting biological activity.
Methods: A Box-Behnken statistical design was applied to optimize scCO extraction conditions-pressure, CO volume, and temperature-to maximize curcuminoid yield.
Neurofibromatosis type 1 (NF1) significantly increases the risk of malignant peripheral nerve sheath tumors (MPNST), a rare and aggressive malignancy for which treatment is clinically challenging. This paper presents the case of a 24-year-old male with an NF1 who developed MPNST with lung metastases. Due to the limited effectiveness of systemic therapy in the treatment of MPNST, the patient underwent radical surgical resection and radiotherapy.
View Article and Find Full Text PDFBackground: The parallel wire technique (PW) is a classic part of the antegrade strategy to open chronic total coronary occlusions (CTO).
Aims: With modern wires and dual-lumen catheters (DLC) the approach has evolved, but this progress had not been evaluated in a contemporary registry of CTO interventions.
Method: This analysis is based on 26,589 CTO procedures performed by 36 operators with > 50 procedures annually between 2015 and 2022.
Article Synopsis
- - Mediastinal yolk sac tumors (YST) are aggressive tumors that are often advanced and difficult to remove at the time of diagnosis, lacking a standardized treatment protocol due to their rarity.
- - The common treatment involves a combination of chemotherapy with cisplatin followed by extensive surgery, as tumors often invade nearby structures like the lungs and heart.
- - This review analyzes existing literature on surgical methods for treating YST, noting the limited information available and aiming to provide clinicians with a better understanding of the complex surgical approaches involved.
This paper presents selected results of theoretical and experimental research into the manufacture of axisymmetric bimetallic components using three-tool skew rolling technology. In the tests, it was assumed that the outer layer would be a material intended for heat treatment. However, low-carbon steel was used for the core.
View Article and Find Full Text PDF