Publications by authors named "J M Witkowski"
Background: Oxidative stress and chronic inflammation, at both the systemic and the central level, are critical early events in atherosclerosis and Alzheimer's disease (AD).
Purpose: To investigate the oxidative stress-, inflammation-, and Tau-phosphorylation-lowering effects of pomegranate polyphenols (PPs) (punicalagin, ellagic acid, peel, and aril extracts).
Methods: We used flow cytometry to quantify the protein expression of proinflammatory cytokines (IL-1β) and anti-inflammatory mediators (IL-10) in THP-1 macrophages, as well as M1/M2 cell-specific marker (CD86 and CD163) expression in human microglia HMC3 cells.
The Effect of Blood Flow Restriction during Low-Load Resistance Training Unit on Knee Flexor Muscle Fatigue in Recreational Athletes: A Randomized Double-Blinded Placebo-Controlled Pilot Study.
J Clin Med
September 2024
Despite the growing popularity of training with a controlled form of vascular occlusion, known as blood flow restriction (BFR) training, in the rehabilitation of orthopedic patients and sports medicine, there remains ample space for understanding the basis of its mechanism. The pilot study assessed the effect of BFR during a low-load resistance training unit on knee flexor muscle fatigue, intending to decide whether a larger trial is needed and feasible. : The study used a prospective, randomized, parallel, double-blind, placebo-controlled design.
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- Globally, while people are living longer, many experience a decline in health due to age-related diseases, highlighting the need for better classification systems to address these issues.
- A consensus meeting with 150 experts established criteria for identifying ageing-related pathologies, requiring a 70% agreement for approval among participants.
- The agreed criteria focus on conditions that progress with age, contribute to functional decline, and are backed by human studies, setting a foundation for future classification and staging efforts.
Article Synopsis
- The study focused on finding the optimal entry point for inserting sacroiliac screws in patients based on their surgical position (prone or supine).
- Using cadavers, researchers tested various entry points for K-wire placement and found that while prone position allowed all entry points to be correct, supine position had issues with the standard entry point.
- The results indicated that for supine surgeries, the best entry point was 2 cm above the standard point, ensuring accurate placement of orthopedic implants.
The measurement of soil water content is a very important factor in plant cultivation, both from an economic and ecological point of view. Proper estimation of moisture content not only allows for proper yields but can also contribute to ecologically appropriate use of fresh water, of which the world's resources are limited. It is important, for example, that the moisture content in the root area of plants is optimal for their growth, while over-watering can result in losses in the form of water, which seeps below the root layer and is lost.
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