Unlabelled: Chronic polymicrobial infections involving and are prevalent, difficult to eradicate, and associated with poor health outcomes. Therefore, understanding interactions between these pathogens is important to inform improved treatment development. We previously demonstrated that is attracted to using type IV pili (TFP)-mediated chemotaxis, but the impact of attraction on growth and physiology remained unknown.
View Article and Find Full Text PDFChronic polymicrobial infections involving and are prevalent, difficult to eradicate, and associated with poor health outcomes. Therefore, understanding interactions between these pathogens is important to inform improved treatment development. We previously demonstrated that is attracted to using type IV pili-mediated chemotaxis, but the impact of attraction on growth and physiology remained unknown.
View Article and Find Full Text PDFBacteria form groups comprised of cells and a secreted polymeric matrix that controls their spatial organization. These groups - termed biofilms - can act as refuges from environmental disturbances and from biotic threats, including phages. Despite the ubiquity of temperate phages and bacterial biofilms, live propagation of temperate phages within biofilms has never been characterized on cellular spatial scales.
View Article and Find Full Text PDFBiofilm formation, including adherence to surfaces and secretion of extracellular matrix, is common in the microbial world, but we often do not know how interaction at the cellular spatial scale translates to higher-order biofilm community ecology. Here we explore an especially understudied element of biofilm ecology, namely predation by the bacterium . This predator can kill and consume many different Gram-negative bacteria, including and .
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