Publications by authors named "J M Weimann"
Background: Cardiovascular disease (CVD) remains the leading cause of death in pregnant and peripartal women in western countries. Physiological changes during pregnancy can lead to cardiovascular complications in the mother; women with pre-existing heart disease may not tolerate these changes well, increasing their susceptibility to adverse cardiovascular outcomes during pregnancy. The aim of this study is to characterize pregnancy-induced changes in cardiac function, biomarker concentrations and cardiovascular outcomes in women with CVD during pregnancy at a tertiary care hospital in Germany.
View Article and Find Full Text PDFIn this paper, we investigate how technology has contributed to experimental economics in the past and illustrate how experimental economics can contribute to technological progress in the future. We argue that with machine learning (ML), a new technology is at hand, where for the first time experimental economics can contribute to enabling substantial improvement of technology. At the same time, ML opens up new questions for experimental research because it can generate previously impossible observations.
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- Patients with mitral regurgitation (MR) and significant mitral annular calcification (MAC) face limited treatment options, making transcatheter mitral valve replacement (TMVR) an interesting area of study.
- The research involved 279 patients, revealing that those with MAC had higher rates of post-procedural bleeding and renal failure but similar overall survival rates and functional improvement compared to those without MAC.
- The findings suggest that while TMVR can be performed in MAC patients, it comes with increased complications, highlighting the need for more research on tailored TMVR devices for this group.
Article Synopsis
- Transcatheter mitral valve replacement (TMVR) is a new treatment for mitral regurgitation that was studied for its effects on heart function using noninvasive pressure-volume loops.
- A study of 26 patients showed improvements in left ventricular (LV) function after TMVR, indicated by a decrease in pressure-volume measures at discharge, but right ventricular (RV) function remained largely unchanged.
- Long-term outcomes suggested that improvements in LV function post-TMVR were linked to lower 1-year rates of all-cause mortality and heart failure hospitalizations.