Publications by authors named "J M W Kirk"
Background: Timely recognition of acute ischemic stroke (AIS) is essential to identify patients who may be eligible for acute intervention. Protocols to streamline systems-based care, such as "stroke alerts" in the emergency department (ED) can safely reduce time-to-care while enhancing safety. However, clinician adherence to stroke alert criteria is poorly described.
View Article and Find Full Text PDFHigh-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.
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- Dry deposition plays a significant role in removing reactive organic carbon from the atmosphere, impacting airborne chemical reactions and transferring this carbon to other environmental systems.
- Using aircraft measurements, researchers found that oil operations can lead to high deposition rates of organic carbon, reaching up to 100 tons per hour, with rapid lifetimes of about 4 hours that can compete with oxidation processes.
- Traditional models for gas-phase deposition may not capture all deposited organic carbon, indicating a need to consider these deposition processes in assessing the effects on freshwater ecosystems, as they contribute significantly to the overall carbon balance compared to terrestrial sources.
SGLT-2i and GLP-1RA are recommended for persons with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD) but are underused in clinical practice. The COORDINATE-Diabetes randomized clincal trial evaluated a multi-faceted intervention to increase the use of evidence-based therapies for reducing cardiovascular risk among participants with diabetes and atherosclerotic cardiovascular disease. This analysis reports the discontinuation rate of SGLT-2i and GLP-1RA in follow up and summarises the clinician-reported reasons underlying these decisions.
View Article and Find Full Text PDFWhen Off-Target the Target: Treating Noncardiomyocytes in Cardiac Laminopathy.
JACC Basic Transl Sci
November 2024