Methanolation of olefins is introduced as a new low-pressure synthetic pathway to C1 elongated alcohols. Formally, HCOH is added to the C=C bond in a 100 % atom efficient manner. Mechanistically, the overall transformation occurs as a tandem reaction sequence by combining the dehydrogenation of methanol to syngas at a CO : H ratio of 1 : 2 with subsequent hydroformylation to the corresponding aldehyde and its final hydrogenation to the alcohol.
View Article and Find Full Text PDFPrebiotics can modulate the gut microbial community composition and function for improved (gut) health and increase resilience against infections. models of the gut facilitate the study of intervention effects on the gut microbial community relevant to health. The mucosa-associated gut microbiota, which thrives in close contact with the host plays a pivotal role in colonization resistance and health.
View Article and Find Full Text PDFThe COVID-19 (SARS-CoV-2) pandemic increased the focus on preventing contamination with airborne pathogens (e.g. viruses, bacteria, and fungi) by reducing their concentration.
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