In vitro cell-transforming capacity of micro- and nanoplastics derived from 3D-printing waste.

The increasing use of plastic polymers in 3D printing applications may lead to human exposure to micro- and nanoplastics (MNPLs), raising concerns regarding adverse health consequences such as cancer induction. Little attention has been given to MNPLs originated at the end of the life cycle of 3D-printed objects because of the mechanical and environmental degradation of plastic waste. This study assessed the carcinogenic potential of secondary MNPLs generated through cryomilling of 3D objects using the validated in vitro Bhas 42 cell transformation assay (CTA).

Genomic Insights Into the Origin, Decline and Recovery of the Once Critically Endangered Iberian Lynx.

The Iberian lynx was at the brink of extinction by the year 2000 but has since then, and thanks to intensive conservation measures, gone through a remarkable recovery, providing a much-welcomed and encouraging conservation success story. Genetic issues have probably contributed to the decline in the past, and the genetic management of inbreeding and genetic diversity is likely contributing to its recent recovery. The species was an early adopter of genetic and genomic approaches, and the combination of an extreme decline, an intensive monitoring and management programme and extensive genomic resources and data makes the Iberian lynx an excellent model for conservation genomics.

Efficacy of cognitive functional therapy for pain intensity and disability in patients with non-specific chronic low back pain: a randomised sham-controlled trial.

Objective: This study investigated the efficacy of cognitive functional therapy (CFT) versus a sham procedure for pain intensity and disability for patients with non-specific chronic low back pain (CLBP).

Methods: This is a randomised sham-controlled trial conducted in a primary care public health service. A total of 152 participants were randomly assigned to the CFT group (n=76) and the sham group (n=76).

Natural attenuation of contamination by hexachlorocyclohexanes in the soils around the Bailín landfill site (Sabiñánigo, Huesca province, NE Spain).

INQUINOSA company dumped waste from lindane production in Sabiñánigo (Huesca, Spain). Lindane is the γ-isomer of hexachlorocyclohexane (γ-HCH), a persistent organic pollutant listed in the Stockholm Convention in 2009. The uncontrolled dumping at two poorly managed landfills (Sardas and Bailín) has become one of the most serious contamination cases in Europe.