Intermediate-Term Oncologic Outcomes of Partial Nephrectomy Versus Cryoablation in Renal Tumors >3 cm: A Propensity Score Matched Analysis.

Purpose: Cryoablation (CA) and partial nephrectomy (PN) are effective nephron-sparing treatments for small renal masses. While guidelines list thermal ablation as an option for tumors <3 cm, limited data compare PN and CA in larger tumors. We compared intermediate-term oncologic outcomes between PN and CA in renal masses >3 cm.

The Effect of Preoperative Tamsulosin on Pediatric Ureteroscopic Access: A Multi-Institutional Experience.

Introduction: The ability to perform flexible ureteroscopy in children may be limited due to a smaller pediatric ureterovesical junction and ureteral diameter. Tamsulosin has been shown to improve success rates of ureteral instrumentation in adults. To date, the efficacy of this medication to facilitate pediatric ureteral access remains unclear.

Modeling conditional distributions of neural and behavioral data with masked variational autoencoders.

Extracting the relationship between high-dimensional neural recordings and complex behavior is a ubiquitous problem in neuroscience. Encoding and decoding models target the conditional distribution of neural activity given behavior and vice versa, while dimensionality reduction techniques extract low-dimensional representations thereof. Variational autoencoders (VAEs) are flexible tools for inferring such low-dimensional embeddings but struggle to accurately model arbitrary conditional distributions such as those arising in neural encoding and decoding, let alone simultaneously.

Manual Dexterity Predictors of Inflatable Penile Prosthesis Success.

Objective: To investigate the ability of preoperative dexterity assessments to predict postoperative success of inflatable penile prosthesis (IPP) placement for erectile dysfunction.

Materials: A timed 9-hole peg test, pinch and grip strength assessment, and Disabilities of the Arm Shoulder and Hand questionnaire were administered during the preoperative visit before IPP placement. In addition to standard preoperative workup, subjective handshake strength was recorded.

The influence of the cytoskeleton on the development and behavior of viral factories in mammalian orthoreovirus.

Cytosolic viral factories (VFs) of mammalian orthoreovirus (MRV) are sites for viral genome replication and assembly of virus progeny. Despite advancements in reverse genetics, the formation and dynamics of VFs still need to be clarified. MRV exploits host cytoskeletal components like microtubules (MTs) throughout its life cycle, including cell entry, replication, and release.