Publications by authors named "J M Varga"

Objectives: An occupational disease (OD) is a disorder or health condition which arises due to work related activities and tasks or is caused by work environment. The impact of ODs on medical and social system may be considered as a very important in relation to mortality, morbidity, and invalidity. The most common ODs in the European Union are musculoskeletal disorders (58% of all ODs in 2015).

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Background: Post-COVID condition (PCC) is characterized by persisting symptoms after the resolution of acute COVID-19. Remdesivir (RDV), a broad-spectrum antiviral drug, has been widely used in patients hospitalized with COVID-19 requiring oxygen therapy. We aimed to evaluate the effects of RDV on PCC by assessing patient-reported and functional outcomes.

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Background: Chronic obstructive pulmonary disease (COPD) is a progressive, inflammatory airway disorder characterized by a gradual decline in lung function and increased oxidative stress. Both oxidative stress and inflammation are central to its pathophysiology, with trace elements such as zinc, copper, iron, manganese, magnesium, selenium, and calcium playing key roles in various cellular processes.

Objective: This article reviews the role of trace elements in COPD, focusing on their involvement in disease pathogenesis and their therapeutic potential.

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Article Synopsis
  • Chronic obstructive pulmonary disease (COPD) is a major health issue that affects airflow and is often linked to smoking, but there's limited research on non-smoking patients.
  • The study involved 6,974 COPD patients from Hungary, examining their demographics, symptoms, treatments, and quality of life, categorizing them as current smokers, former smokers, or never smokers.
  • Results showed that never smokers had a better quality of life, lung function, and overall health compared to smokers, despite having more comorbidities, highlighting the need for specific treatment strategies for these patients.
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Article Synopsis
  • * Researchers conducted a cross-sectional analysis involving 489 SSc-ILD patients, classifying their HRCTs to determine the presence of UIP.
  • * Results showed that while MUC5B was not linked to UIP patterns, the FAM13A gene was associated with an increased likelihood of definite UIP in these patients, suggesting different genetic influences compared to idiopathic pulmonary fibrosis (IPF) and rheumatoid arthritis-related ILD.
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