Publications by authors named "J M Tapanainen"

Article Synopsis
  • The study aimed to investigate the link between premenopausal hyperandrogenaemia (HA) and the risk of hypertension and cardiovascular diseases (CVDs) in a cohort of 5,889 women.
  • The findings showed that higher levels of testosterone and free androgen index were linked to increased blood pressure and a higher likelihood of hypertension at ages 31 and 46, as well as an increased risk of CVD events over 22 years, particularly before adjusting for body mass index (BMI).
  • Despite the initial associations, the significance of the results diminished when accounting for BMI, highlighting the need for further research with a more diverse population and longer follow-up to better understand these relationships.*
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Stanniocalcin (STC) 1 and 2 serve as antihyperglycemic polypeptide hormones with critical roles in regulating calcium and phosphate homeostasis. They additionally function as paracrine and/or autocrine factors involved in numerous physiological processes, including female reproduction. STC1 and STC2 contribute to the pathophysiology of several diseases, including female infertility- and pregnancy-associated conditions, and even tumorigenesis of reproductive organs.

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The beneficial effects of physical activity (PA) on gut microbiome have been reported, nevertheless the findings are inconsistent, with the main limitation of subjective methods for assessing PA. It is well accepted that using an objective assessment of PA reduces the measurement error and also allows objective assessment of sedentary behavior (SB). We aimed to study the associations between accelerometer-assessed behaviors (i.

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Objective: This population-based follow-up study investigated register-based disease diagnoses and medication use up till age of 50 years among women with polycystic ovary syndrome (PCOS) that were identified from a population-based birth cohort.

Design: Population-based longitudinal cohort study.

Patients: Women reporting oligo/amenorrhea and hirsutism at age 31 and/or who were diagnosed with PCOS by a physician by age 46 (n = 244) and women without PCOS symptoms or diagnosis (n = 1556) in the Northern Finland Birth Cohort 1966.

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Introduction: The incidence of gestational diabetes mellitus (GDM) is globally increasing, and it has been associated with later type 2 diabetes, metabolic syndrome (MetS), and cardiovascular disease (CVD). However, long-term population-based studies investigating common CVD risk factors years after pregnancy are lacking. To evaluate the future mortality and morbidity in cardiovascular and metabolic diseases, we conducted a thorough investigation of midlife risk factors in women with and without previous GDM.

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