Publications by authors named "J M Sobrino-Marquez"

Introduction And Objectives: Our aim was to describe the characteristics and outcomes of heart transplants in Spain.

Methods: We analyzed trends in recipient and donor characteristics, recipient-donor interaction, surgical procedures, immunosuppression, and outcomes of patients included in the Spanish heart transplant registry from 2014 to 2023. Changes in survival were analyzed using the Kaplan-Meier method.

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Transcatheter aortic valve replacements have become a good option for patients with aortic valve disease and high surgical risk. Thromboembolism is reported as a relatively common complication of Transcatheter aortic valve replacement. This risk may be increased in patients who have left ventricular assist devices, as valve motion is drastically reduced.

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The bicaval transcatheter prosthesis (TricValve) allows the treatment of cava reflux in patients with severe tricuspid regurgitation and high surgical risk. It consists of the implantation of 2 self-expanding valves in both vena cava without directly approaching the native tricuspid valve. Heart transplantation in this setting may require some modifications compared with the conventional bicaval technique.

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Background: Cardiac allograft vasculopathy (CAV) is a high-incident complication of heart transplant (HT) and is the leading cause of death beyond the first post-HT year. Traditional risk factors have been related to CAV development. Elevated lipoprotein (a) (Lp[a]) is an independent, genetic, and causal risk factor for cardiovascular disease; nonetheless, its association with the development or worsening of CAV in HT has not been firmly established.

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Article Synopsis
  • The Spanish heart transplant registry provides annual updates, with the latest focusing on data from 2022 regarding clinical characteristics and survival outcomes of heart transplants.
  • In 2022, there were 311 heart transplants, marking a 3.0% increase from 2021, while demographic and clinical characteristics remained consistent with previous years.
  • Over the past decade, survival rates have stabilized at 1 year (81.4%) and 3 years (73.4%), with a noted decrease in urgent transplants and the use of circulatory support devices.
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