Publications by authors named "J M Sheppard"
Operant keypress tasks in a reinforcement-reward framework where behavior is shaped by its consequence, show lawful relationships in human preference behavior (i.e., approach/avoidance) and have been analogized to "wanting".
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- An international network is being developed to survey scientists continuously, gathering extensive datasets about their opinions over time.
- Local coordinators at participating institutions will send out brief survey invitations to scientists, utilizing a simple 10-second survey format with a single statement and a five-point Likert scale.
- A recent study successfully engaged over 20,000 scientists, receiving 6,807 responses, which demonstrates the feasibility of quickly measuring global scientific opinion, potentially aiding in policy-making and enhancing public understanding.
Purpose: This pooled analysis of two pivotal studies (ESSENCE-1 and ESSENCE-2) evaluated treatment effects of a water-free ciclosporin 0.1% solution in dry eye disease (DED) patients in the overall population and in subgroups according to sex, age, and baseline severity of disease.
Methods: In these randomized, multicenter, double-masked, vehicle-controlled studies patients received ciclosporin 0.
Background: Nocturnal home blood pressure monitoring (HBPM) may identify people at higher cardiovascular disease (CVD) risk than expected.
Objectives: The aim of this study was to examine the association between office-masked nocturnal hypertension, defined by HBPM, and CVD risk in a clinical practice-based population.
Methods: Prospective observational study including Japanese high cardiovascular-risk participants.
Background: Dry eye disease (DED) is commonly caused by excessive tear film evaporation due to Meibomian gland dysfunction (MGD). There is a need for DED treatment options that address tear evaporation and benefit patients across a broad range of demographic and disease characteristics. This study evaluated treatment effects of perfluorohexyloctane ophthalmic drop (formerly NOV03) in the pooled dataset from 2 pivotal clinical trials in patients with DED associated with MGD, both in the overall population and in patient subgroups based on sex, age, and baseline severity of eye dryness.
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