Publications by authors named "J M Semahore"
Article Synopsis
- The Xpert MTB/RIF assay is widely used to quickly diagnose tuberculosis and identify rifampicin resistance, but this study examines how often false-positive rifampicin resistance results occur.
- Conducted in Rwanda, the study involved patients with initial positive results and included repeat testing and advanced sequencing to clarify actual resistance status.
- Of the 154 patients retested, 47% were found to have false-positive results for rifampicin resistance, while a subset of those with true resistance also had issues being confirmed by the initial Xpert test.
In 2005, in response to the increasing prevalence of rifampicin-resistant tuberculosis (RR-TB) and poor treatment outcomes, Rwanda initiated the programmatic management of RR-TB, including expanded access to systematic rifampicin drug susceptibility testing (DST) and standardised treatment. To describe trends in diagnostic and treatment delays and estimate their effect on RR-TB mortality. Retrospective analysis of individual-level data including 748 (85.
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