Publications by authors named "J M Rusnak"
This study investigates the prognosis of acute decompensated heart failure (ADHF) on admission (i.e., primary ADHF) as compared to ADHF onset during course of hospitalization (i.
View Article and Find Full Text PDF: The study investigates sex-related differences and outcomes in unselected patients undergoing invasive coronary angiography (CA). Sex-based differences with regard to baseline characteristics and management of patients with cardiovascular disease have yet been demonstrated. However, their impact on long-term outcomes in unselected patients undergoing CA remains unknown.
View Article and Find Full Text PDFBackground: There is limited data regarding the influence of lung compliance on the outcome of patients with cardiogenic shock (CS). Thus, a registry study was conducted to assess the prognostic influence of lung compliance in invasively ventilated patients with CS.
Methods: Hospital records for consecutive invasively ventilated CS-patients from June 2019 to May 2021 were collected into a prospective registry.
Background: Nirmatrelvir/ritonavir (NMV/r) is an oral antiviral treatment for mild to moderate COVID-19.
Methods: This phase 2/3, double-blind, randomized (1:1) study assessed oral NMV/r 300 mg/100 mg versus placebo every 12 hours for 5 days in high-risk, unvaccinated, nonhospitalized, symptomatic adults with COVID-19 from 343 sites across 21 countries. In testing the primary endpoint of COVID-19‒related hospitalization and all-cause deaths and key secondary endpoints including symptom duration and COVID-19‒related medical visits, Type I error was controlled with prespecified sequential testing and the Hochberg procedure.
Article Synopsis
- The study evaluates the impact of right bundle branch block (RBBB) and left bundle branch block (LBBB) on the prognosis of patients with cardiogenic shock (CS), focusing on 30-day mortality rates.
- It involved 248 adult patients from an ICU in Germany, finding that those with RBBB had the highest mortality at 72.5%, compared to 52.9% for LBBB and 50.0% for no block.
- RBBB significantly predicted increased mortality even after adjusting for key health indicators, while LBBB showed no significant association with mortality outcomes.