Publications by authors named "J M Rosner"
Hip abductors are essential for hip function. To understand abduction weakness, it is important to know which muscles contribute to abduction force. Our aim was to investigate the effects of an experimentally induced weakness of the different muscles (tensor fasciae latae [TFL], gluteus medius and minimus (Gmed/min), gluteus maximus [Gmax]) on the abduction force.
View Article and Find Full Text PDFBackground: Magnetic resonance imaging may suggest spinal cord compression and structural lesions in degenerative cervical myelopathy (DCM) but cannot reveal functional impairments in spinal pathways. We aimed to assess the value of contact heat evoked potentials (CHEPs) in addition to MRI and hypothesized that abnormal CHEPs may be evident in DCM independent of MR-lesions and are related to dynamic mechanical cord stress.
Methods: Individuals with DCM underwent neurologic examination including segmental sensory (pinprick, light touch) and motor testing.
This chapter aims to review the current pharmacological options for neuropathic pain treatment, their mechanisms of action, and future directions for clinical practice. Achieving pain relief in neuropathic pain conditions remains a challenge in clinical practice. The field of pharmacotherapy for neuropathic pain has encountered significant difficulties in translating substantial advances in our understanding of the underlying pathophysiological mechanisms into clinically effective therapies.
View Article and Find Full Text PDFArticle Synopsis
- - The study explores the relationship between pain habituation (how pain response decreases over time) and conditioned pain modulation (CPM), which is a measure of the body’s ability to manage pain, in 45 healthy participants.
- - Pain habituation was evaluated using subjective pain ratings and objective measures (CHEP and SSR) during heat stimuli, revealing significant variability in participants’ responses, particularly in subjective ratings.
- - It was found that while subjective pain habituation correlated with cold-induced CPM effects, this correlation did not hold for other CPM measures, suggesting that subjective and objective pain responses may reflect different aspects of how our body modulates pain.
Article Synopsis
- - The study examined if pain habituation measures could be potential indicators of central sensitization in chronic pain patients compared to healthy controls (HC), involving 93 patients and 60 controls and using contact-heat stimuli.
- - Results showed no significant differences in pain habituation between chronic pain patients and HC, even in those with clear signs of central sensitization; however, patients had longer latencies in contact-heat evoked potentials (CHEP) and sympathetic skin responses (SSR).
- - The findings suggest that pain habituation may remain intact in chronic pain patients, questioning its role as a reliable marker for central sensitization and highlighting the need for further research on pain mechanisms using advanced neurophysiological methods.