Biomarkers.

Background: The diagnostic capability of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) is well established, but few studies have explored the utility of repeating scans, especially when using semi-quantification methods to analyze the decrement between them.

Methods: We retrospectively selected all patients at our clinic submitted to two or more FDG-PETs. The initial and final FDG-PET of each patient underwent semi-quantitative analysis using the CortexID® Suite software (GE Healthcare) for 26 pre-determined regions normalized for global cortical uptake.

Alzheimer's Imaging Consortium.

Background: The diagnostic capability of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) is well established, but few studies have explored the utility of repeating scans, especially when using semi-quantification methods to analyze the decrement between them.

Methods: We retrospectively selected all patients at our clinic submitted to two or more FDG-PETs. The initial and final FDG-PET of each patient underwent semi-quantitative analysis using the CortexID® Suite software (GE Healthcare) for 26 pre-determined regions normalized for global cortical uptake.

Computerized adaptive testing for PRWHE measurements using domains of pain and motor function.

The Patient-Rated Wrist and Hand Evaluation is an outcome measure for patients with conditions affecting the wrist or hand. We evaluated the structural validity of the Patient-Rated Wrist and Hand Evaluation using psychometric techniques, then developed computerized adaptive testing algorithms. Factor analysis found two health constructs consistent with 'Pain' and 'Motor Function'.

Iatrogenic intramural esophageal hematoma during EUS-B-FNA procedure.

Background: Esophageal ultrasound with bronchoscope fine needle aspiration (EUS-B-FNA) is a valuable tool for the diagnosis and staging of lung cancer, complementing endobronchial lung ultrasound (EBUS). While generally considered safe, there is a notable lack of comprehensive knowledge within the interventional pulmonology community regarding potential complications.

Case Presentation: We present a case involving a 66-year-old male with squamous cell lung carcinoma undergoing mediastinal staging.

Immunoprophylaxis with MV140 Is Effective in the Reduction of Urinary Tract Infections-A Prospective Real-Life Study.

Background/objectives: Urinary tract infections (UTI) represent a highly frequent and debilitating disease. Immunoactive prophylaxis, such as the polyvalent bacterial whole-cell-based sublingual vaccine MV140, have been developed to avoid antibiotic use. However, the effectiveness of this tool in the Portuguese population is still unknown.