Efficacy and Budget Impact of a Tailored Psychological Intervention Program Targeting Cancer Patients With Adjustment Disorder: A Randomised Controlled Trial.

Background: Evidence on the efficacy of psychological interventions targeting cancer patients diagnosed with an adjustment disorder is scarce.

Aims: This study aimed to investigate the efficacy and budget impact of a tailored psychological intervention program (AD-program) targeting cancer patients with adjustment disorder (AD).

Methods: Patients (n = 59) were randomised to the intervention or control group.

The single-cell immune profile throughout gestation and its potential value for identifying women at risk for spontaneous preterm birth.

Precisely timed immune adaptations, observed in the maternal circulation, underpin the notion of an immune clock of human pregnancy that supports its successful progression and completion at delivery. This immune clock is divided into three immunological phases, with the first phase starting at the time of conception and implantation, shifting into the second phase that supports homeostasis and tolerance throughout pregnancy, and culminating in the last phase of labor and parturition. Disruptions of this immune clock are reported in pregnancy complications such as spontaneous preterm birth.

Assessing Fear of Cancer Recurrence among Adolescents and Young Adults: The Portuguese Validation and Psychometric Assessment of the "Fear of Cancer Recurrence 7" Scale.

Introduction: Adolescents and young adults with cancer experience high levels of fear of cancer recurrence (FCR), negatively impacting their lives. However, no measure has been validated worldwide to assess FCR levels among these young people. This study aims to validate the FCR7, a scale that measures FCR, for the Portuguese population of adolescents and young adults.

Soluble CD14 and IL-12p70 on early ART predict HIV load setpoint after treatment interruption.

Objective: After analytical treatment interruption (ATI), viral rebound occurs in most people with HIV. The time to viral rebound (TTVR) is likely determined by the properties of the viral reservoir as well as the anti-viral immune response. Soluble biomarkers of immune activation may be predictive of TTVR and plasma viral load (pVL) setpoint after ATI.

Placental pathology is associated with lower quality fidgety movements in preterm infants.

Background: Preterm infants are at risk for neurodevelopmental disabilities later in life, like motor delays and cerebral palsy (CP). The placenta plays a critical role throughout pregnancy, particularly in preterm birth. Our aim is to explore the relation between placental lesions and accurate predictors of neurodevelopmental outcomes in preterm infants.