Publications by authors named "J M Peman"
Article Synopsis
- Fungemia poses a significant risk in ICUs, maintaining high mortality rates despite better treatment options, and yeast colonization is a key independent risk factor needing more research.
- In an 8-year study involving 38,017 samples from 3206 patients, researchers investigated colonization patterns, the effectiveness of the Colonisation Index (CI) and Corrected Colonisation Index (CCI), and candidemia risks linked to various yeast species.
- Results indicated increased colonization rates with prolonged hospital stays and highlighted that while yeast colonization has high sensitivity and negative predictive value, its predictive power is relatively low, underscoring the need for weekly surveillance to enhance fungemia risk assessment and antifungal management.
Background: Invasive pneumococcal disease (IPD) remains a significant concern among children under 5, despite vaccination efforts. This study assessed IPD prevalence and associated risks in pediatric population.
Methods: An observational, retrospective, multicenter study in Comunidad Valenciana, Spain, of IPD cases in children under 13 from January 2012 to September 2022.
is an emerging, multidrug-resistant yeast that causes systemic infections, mainly in hospitalized or immunosuppressed patients. This pathogen has a high mortality and morbidity rate. This study aims to evaluate the antifungal potential of micafungin (MICA) encapsulated in a nanoemulsion (NEM) against four clades of and other non- species.
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- This study aims to quickly and accurately detect the Y132F ERG11p mutation in Candida parapsilosis isolates and to analyze genetic diversity among these isolates for better tracking of fluconazole resistance.!* -
- The research involved 223 isolates from patients across 20 hospitals in Spain and Italy, using newly optimized PCR methods that require no DNA extraction and provide results in as little as 1.5 hours.!* -
- The findings confirm both PCR methods have 100% specificity and sensitivity, with Scheme 1 showing greater genetic diversity compared to Scheme 2, suggesting the use of specific microsatellite markers for better genotyping of resistant strains.!*