A higher mitochondrial content is associated with greater oxidative damage, oxidative defenses, protein synthesis and ATP turnover in resting skeletal muscle.

An unavoidable consequence of aerobic metabolism is the production of reactive oxygen species (ROS). Mitochondria have historically been considered the primary source of ROS; however, recent literature has highlighted the uncertainty in primary ROS production sites and it is unclear how variation in mitochondrial density influences ROS-induced damage and protein turnover. Fish skeletal muscle is composed of distinct, highly aerobic red muscle and anaerobic white muscle, offering an excellent model system in which to evaluate the relationship of tissue aerobic capacity and ROS-induced damage under baseline conditions.

Reduced graphene oxide biosensor platform for the detection of NT-proBNP biomarker in its clinical range.

Reduced graphene oxide (rGO) thin films can be exploited as highly sensitive transducer layers and integrated in interdigital micro-electrode systems for biosensing processes. The distinctive bipolar characterisitics of rGO thin films can be modulated by a very low external electric field due to the electrostatic charges of biomolecules. These charges lead to a fast response in the readout signals of rGO based ion sensitive field-effect transistors (ISFETs).

Fabrication of a custom abutment for a wide-diameter implant in a situation with limited interocclusal space.

This article illustrates a technique to solve the esthetic and functional challenges of restoring implants in situations with limited interocclusal clearance. As manufactured, some wide implants lack a gold cylinder abutment that attaches directly to the implant. Instead, an intermediate abutment is provided with the system.

A technique for verifying the accuracy of a soldered prosthesis with intraoral records.

The art of soldering dental ceramic alloys has always been one of the many challenges faced by the dental technologist. This article presents a method for verifying the accuracy of a postsoldered prosthesis as it relates to intraoral indexes taken before a soldering procedure. The advantage of this technique to the dentist is saved chair time.

Carbon-13 nuclear magnetic resonance studies of myocardial glycogen metabolism in live guinea pigs.

Myocardial glycogen metabolism was studied in live guinea pigs by 13C NMR at 20.19 MHz. Open-chest surgery was used to expose the heart, which was then positioned within a solenoidal radio frequency coil for NMR measurements.