Synthesis and optimization of biobased carbon adsorbent monoliths from chitosan-polybenzoxazine for efficient CO capture.

The present study introduces a novel method for the preparation of a CO carbon adsorbent derived from biobased precursors. Porous carbon adsorbents were synthesized through the carbonization and thermal activation of biobased chitosan-polybenzoxazine. First, the study explored the influence of varying amounts of the key polymer precursors, lysine (0.

Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.

Precision medicine approaches to cancer treatment aim to exploit genomic alterations that are specific to individual patients to tailor therapeutic strategies. Yet, some targetable genes and pathways are essential for tumor cell viability even in the absence of direct genomic alterations. In underrepresented populations, the mutational landscape and determinants of response to existing therapies are poorly characterized because of limited inclusion in clinical trials and studies.

Unusual Presentation of Advanced Urothelial Cancer in a Young Patient.

Background/aim: Urothelial carcinoma, common in older adults, is rare in younger populations and even less common in the prostatic urethra. Advanced disease is typically managed with platinum-based chemotherapy, immune checkpoint inhibitors, and targeted therapies. However, rare presentations in young patients with aggressive disease highlight the need for innovative and personalized treatment strategies.